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My colleagues and I just published the first report of cerebral toxoplasmosis in a patient with myasthenia gravis and the under-recognised TWI/Good’s syndrome.
Click here to access the article online
My colleague Dr Ari Murad has just published a new Clinical Immunology & Allergy Self Assessment book available via kindle or iBooks. This would be a good resource for anyone interested in learning advanced immunology:
The class of antiretrovirals that acts at the step indicated by the large red arrow is:
c) Fusion inhibitors
d) Protease Inhibitors
e) Integrase inhibitors
Click here for answer
T-cell immunodeficiency is most commonly associate with recurrence of which?
a) Lupus-like syndrome
b) Varicella zoster virus
c) Neisseria meningitidis
d) Haemophilus influenzae
Click here for answer
A patient is newly diagnosed with HIV infection. CD4+ T-cell count is 700 cells/microL (RR 500-1200) and HIV viral load is >1000000 copies/mL. In regard to management which statement is CORRECT?
a) There are benefits to commencing Anti-retroviral therapy (ART) when CD4+ T-cell count is >500 cells/mL.
b) If the virus is CCR5-tropic then Maraviroc should be prescribed
c) The patient should be advised to take ART on alternate months i.e. 1 month on therapy and 1 month off
d) The patient should be commenced on PJP prophylaxis
e) The patient is an elite controller
Click here for Answer
A few slides on the rare Good’s Syndrome/Thymoma with immunodeficiency. Click on the link below:
I have updated the notes on common variable immunodeficiency (CVID). Click on the link below:
The body makes 66mg/kg/day of IgA. Learn more about the biology of this antibody and IgA deficiency here: